In my main folder create new folders automatically. I delete them continuously but after some time they come again. How to remove NewFolder.exe and in future how can i prevent my laptop from these kind of Malwares?

NewFloder.exe is an executable file, judging by the extension - don't open it!

What do you mean by "main folder" - C:\Windows ?
The main drive like C:\ ; D:\ ; E:\ (whatever your disk drive letters are...) ?
Оr lots of folders that are main for each program etc. ?

We will need more information, but it sure does sound like malware...

Yeah, main folder mean Drives C:/,D:/,E:/ etc. Every Drive and Folders in the Drives have these kind of folders like "new folder".

Well, Tabeer, it does sound like a malicuous program caused this.

First, do you have an anti-malware program? If you do - run a full scan of your PC.
If you don't - get such a program and scan. In any case, you need such a program at all times, so malware doesn't run wild.

Second, it seems that this malware might have messed up with registry entries
and that would explain why those files are created and keep getting back.

Third, if the anti-malware scan doesn't fix your problem, or you are somehow prevented from downloading such - write back.
I will try to guide you to what you should do next.

You could also go to your Task Manager and see if you have some process running like: "newfolder.exe".

@Execute, I installed Microsoft Essential, I use to run as full scan after 3 to 4 days but it catch nothing. sometime when i install a new program, it detect malware and try to delete them.

@Tabeer, try with another anti-malware program, if MSE is not helping you. And 3-4 days sounds like a lot, I guess this malware is taking some of your computer memory.

Also, as dealing with the registry can get messy, try installing a Registry cleaner also, to see if it can fix the issue.

Did you search for a newfolder.exe process or service? If you haven't - search your PC for that and try to disable and delete it.

Best Regards,
Execute

I try Mcafee and Avira for cleaning, both show "new floder.exe" and I delete "new floder.exe" with these software but after few days "new floder.exe" came again.

Its very frustrating, I tried your solution but could not get rid off "new folder.exe" virus. I'm sure there must be a software or application that'll solve my problem. thanks you tried to help me at least.

Hello Tabeer, I believe you misunderstood me. After you scan you PC with FarBar you should upload the files as attachments to your reply in this topic so that we may see where the issue might be and help you fix it. Check the steps carefully and follow them.
Regards,
Never

@Tabeer, you can first try giving us more information by following never's guide.
Also, I have answered your question in the other related topic (which was moved by the Admin).
You can find it by clicking on this link.